Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GART | P22102 | 5/20 | 0.38 |
| ▸ | DHFR | P00374 | 3/20 | 0.36 |
| ▸ | ATIC | P31939 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494144 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL9534079 | 0.88 | GART (0.49) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL9534086 | 0.88 | GART (0.49) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL9535283 | 0.84 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL9535276 | 0.84 | KDM4E (0.40) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL10479164 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL10479162 | 0.84 | KDM4E (0.37) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL10404862 | 0.83 | GART (0.46) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL10404860 | 0.83 | GART (0.46) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL9050424 | 0.80 | GART (0.48) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4684653-A | ANTITUMOR AGENTS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1987-08-04 | — | — | US | claimed |
| US-4845216-A | ANTITUMOR AGENTS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1989-07-04 | — | — | US | disclosed |
| US-4684653-A | ANTITUMOR AGENTS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1987-08-04 | — | — | US | disclosed |