Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.33 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494180 | 0.97 | PNMT (0.45) | PNMTTSHRHPGDL3MBTL1BCL2L1 | |
| SCHEMBL10494187 | 0.89 | PNMT (0.47) | PNMTTSHRBCHEDRD4CES1 | |
| SCHEMBL30701052 | 0.83 | BCL2L1 (0.50) | TSHRBCL2L1BADHSD11B1SMN1; SMN2 | |
| SCHEMBL11005883 | 0.83 | BCL2L1 (0.50) | TSHRBCL2L1BADHSD11B1SMN1; SMN2 | |
| SCHEMBL10914530 | 0.83 | PNMT (0.67) | PNMTTSHRHPGDL3MBTL1BCL2L1 | |
| SCHEMBL10494159 | 0.83 | PNMT (0.45) | PNMTTSHRHPGDL3MBTL1BCL2L1 | |
| SCHEMBL11000510 | 0.83 | PNMT (0.45) | PNMTTSHRHPGDL3MBTL1BCL2L1 | |
| SCHEMBL9875183 | 0.80 | PNMT (0.68) | PNMTHPGDMAOABCHEDRD4 | |
| SCHEMBL19354160 | 0.80 | BCL2L1 (0.45) | TSHRBCL2L1BADBCHESMN1; SMN2 | |
| SCHEMBL10494233 | 0.79 | PNMT (0.45) | PNMTTSHRHPGDL3MBTL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4837307-A | [1,1'-biphenyl]compounds having a 2,2'-(alkyl)bridge and a 3-yl(substituted)methyl substituent | FMC CORPORATION (US) | 1989-06-06 | — | — | US | claimed |
| US-4837307-A | [1,1'-biphenyl]compounds having a 2,2'-(alkyl)bridge and a 3-yl(substituted)methyl substituent | FMC CORPORATION (US) | 1989-06-06 | — | — | US | disclosed |