Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10494194 | 0.87 | ELANE (0.74) | ELANE | |
| SCHEMBL10494137 | 0.85 | ELANE (0.62) | ELANE | |
| SCHEMBL10494153 | 0.83 | ELANE (0.72) | ELANE | |
| SCHEMBL10494160 | 0.83 | ELANE (0.72) | ELANE | |
| SCHEMBL11036240 | 0.80 | ELANE (0.48) | ELANE | |
| SCHEMBL10494181 | 0.76 | ELANE (0.66) | ELANE | |
| SCHEMBL10494163 | 0.76 | ELANE (0.66) | ELANE | |
| SCHEMBL10494142 | 0.76 | ELANE (0.66) | ELANE | |
| SCHEMBL13671134 | 0.76 | ELANE (0.87) | ELANE | |
| SCHEMBL125979 | 0.76 | ELANE (0.87) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4812474-A | ELASTASE INHIBITORY ANTIINFLAMMATORY AGENT | G. D. SEARLE & CO. (US) | 1989-03-14 | — | — | US | disclosed |
| US-4735964-A | ELASTASE INHIBITORS; ANTI INFLAMMATORY AGENTS | G. D. SEARLE & CO. (US) | 1988-04-05 | — | — | US | disclosed |
| US-4603144-A | Kojic acid ether-ester derivatives | G. D. SEARLE & CO. (US) | 1986-07-29 | — | — | US | disclosed |