Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 8/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8130917 | 1.00 | RAB9A (0.56) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL8129293 | 1.00 | RAB9A (0.56) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL8130767 | 1.00 | RAB9A (0.56) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL8130837 | 1.00 | RAB9A (0.56) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL6900551 | 0.94 | RAB9A (0.58) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL8127181 | 0.92 | ELANE (0.56) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL3567584 | 0.89 | RAB9A (0.59) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL4420862 | 0.85 | RAB9A (0.52) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL6401443 | 0.85 | RAB9A (0.53) | RAB9ANPC1CYP1A2CYP2C19RECQL | |
| SCHEMBL8130017 | 0.84 | RAB9A (0.49) | RAB9ANPC1CYP1A2CYP2C19RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4812474-A | ELASTASE INHIBITORY ANTIINFLAMMATORY AGENT | G. D. SEARLE & CO. (US) | 1989-03-14 | — | — | US | disclosed |
| US-4735964-A | ELASTASE INHIBITORS; ANTI INFLAMMATORY AGENTS | G. D. SEARLE & CO. (US) | 1988-04-05 | — | — | US | disclosed |
| US-4603144-A | Kojic acid ether-ester derivatives | G. D. SEARLE & CO. (US) | 1986-07-29 | — | — | US | disclosed |
| EP-0171814-A1 | Kojic acid ether-ester derivatives | G.D. Searle & Co. (US) | 1986-02-19 | — | — | EP | disclosed |