Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | HK2 | P52789 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5811859 | 0.79 | BCL2 (0.52) | HSD17B10KMT2ACYP3A4MEN1HPGD | |
| SCHEMBL16431787 | 0.78 | MAPT (0.38) | HSD17B10KMT2ACYP3A4MEN1HPGD | |
| SCHEMBL16225752 | 0.73 | EGFR (0.58) | HSD17B10KMT2ACYP3A4MEN1HPGD | |
| SCHEMBL27823421 | 0.70 | IDO1 (0.41) | CYP3A4HK2 | |
| SCHEMBL5809753 | 0.69 | PIM1 (0.59) | HSD17B10KMT2ACYP3A4MEN1HPGD | |
| SCHEMBL10494226 | 0.69 | KDM4E (0.41) | HSD17B10KMT2ACYP3A4MEN1HPGD | |
| Flaviolin SCHEMBL703160 | 0.68 | BCL2 (0.52) | HSD17B10KMT2ACYP3A4MEN1HPGD | |
| SCHEMBL22139375 | 0.68 | PTGES (0.33) | HSD17B10KMT2ACYP3A4MEN1HPGD | |
| SCHEMBL31467748 | 0.68 | KDM4E (0.36) | HSD17B10KMT2ACYP3A4MEN1HPGD | |
| SCHEMBL1258932 | 0.68 | CYP3A4 (0.64) | KMT2ACYP3A4MEN1HPGDPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4888026-A | HAIR DYES; OXIDATION RESISTANCE | L'OREAL (FR) | 1989-12-19 | — | — | US | claimed |
| US-4888026-A | HAIR DYES; OXIDATION RESISTANCE | L'OREAL (FR) | 1989-12-19 | — | — | US | disclosed |