Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13868129 | 0.97 | DNM1 (0.39) | DNM1ALDH1A1TSHRTDP1CA12 | |
| Hydrochloric Acid SCHEMBL10495158 | 0.94 | DNM1 (0.42) | DNM1ALDH1A1TSHRTDP1CA12 | |
| Bromide SCHEMBL10495260 | 0.84 | DNM1 (0.50) | DNM1ALDH1A1TSHRMAPT | |
| Bromide SCHEMBL10495169 | 0.82 | DNM1 (0.54) | DNM1MAPT | |
| SCHEMBL24030556 | 0.81 | DNM1 (0.48) | DNM1ALDH1A1TSHR | |
| Bromide SCHEMBL10495210 | 0.80 | DNM1 (0.58) | DNM1TDP1MAPT | |
| Bromide SCHEMBL10495249 | 0.80 | DNM1 (0.58) | DNM1TDP1MAPT | |
| Bromide SCHEMBL10495219 | 0.80 | DNM1 (0.58) | DNM1TDP1MAPT | |
| Bromide SCHEMBL10495193 | 0.80 | DNM1 (0.58) | DNM1TDP1MAPT | |
| Bromide SCHEMBL10495147 | 0.80 | DNM1 (0.58) | DNM1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871874-A | Process for producing dienes | ETHYL CORPORATION (US) | 1989-10-03 | — | — | US | disclosed |