Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770766 | 0.78 | CYP1A2 (0.47) | GAAMAPTKDM4ELMNAHTT | |
| SCHEMBL9635890 | 0.75 | CYP3A4 (0.38) | GAAMAPTKDM4ETSHRPOLB | |
| SCHEMBL4234168 | 0.74 | CGAS (0.35) | GAAMAPTKDM4ELMNAHTT | |
| SCHEMBL10288226 | 0.73 | MAPT (0.55) | GAAMAPTKDM4ELMNAHTT | |
| SCHEMBL10777187 | 0.72 | MAPT (0.59) | GAAMAPTKDM4ELMNAHTT | |
| SCHEMBL23051401 | 0.72 | HRH1 (0.47) | HTR2ASLC6A4MEN1KMT2ACYP1A2 | |
| SCHEMBL18048819 | 0.70 | MAPT (0.41) | GAAMAPTKDM4ELMNAHTT | |
| SCHEMBL3964972 | 0.70 | TDP1 (0.48) | GAAMAPTKDM4ELMNAHTT | |
| SCHEMBL5061017 | 0.68 | CYP19A1 (0.49) | GAAMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL1887779 | 0.68 | MAPT (0.50) | GAAMAPTKDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863924-A | N-benzoyl urea compounds, antitumorous compositions containing them | ISHIHARA SANGYO KAISHA LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0226104-A2 | N-Benzoyl urea compounds, antitumorous compositions containing them, and process for their preparation | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-06-24 | — | — | EP | disclosed |