Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | P4HB | P07237 | 1/20 | 0.54 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.54 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 10/20 | 0.52 |
| ▸ | CA1 | P00915 | 9/20 | 0.52 |
| ▸ | CA9 | Q16790 | 8/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 6/20 | 0.51 |
| ▸ | CA4 | P22748 | 6/20 | 0.51 |
| ▸ | CA5A | P35218 | 6/20 | 0.51 |
| ▸ | CA7 | P43166 | 6/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.51 |
| ▸ | CA6 | P23280 | 4/20 | 0.51 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10495788 | 1.00 | TSHR (0.57) | TSHRP4HBPDIA4PDIA3CA2 | |
| SCHEMBL10495776 | 1.00 | TSHR (0.57) | TSHRP4HBPDIA4PDIA3CA2 | |
| SCHEMBL10359936 | 0.85 | TSHR (0.64) | TSHRCA2CA1CA9CYP2D6 | |
| SCHEMBL8722654 | 0.85 | TSHR (0.64) | TSHRCA2CA1CA9CYP2D6 | |
| SCHEMBL8722653 | 0.85 | TSHR (0.64) | TSHRCA2CA1CA9CYP2D6 | |
| SCHEMBL23742930 | 0.85 | TSHR (0.64) | TSHRCA2CA1CA9CYP2D6 | |
| SCHEMBL15514610 | 0.85 | TSHR (0.64) | TSHRCA2CA1CA9CYP2D6 | |
| Catechol SCHEMBL6657117 | 0.84 | TSHR (0.62) | TSHRP4HBPDIA4PDIA3CA2 | |
| SCHEMBL6867867 | 0.83 | LMNA (0.62) | TSHRCA2CA1CA9CYP2D6 | |
| SCHEMBL6859193 | 0.83 | LMNA (0.62) | TSHRCA2CA1CA9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874852-A | Glycosidation catalust and process for preparing glycoside derivatives | NIPPON FINE CHEMICAL CO., LTD. (JP) | 1989-10-17 | — | — | US | disclosed |
| EP-0263027-A1 | Glycosidation catalyst and process for preparing glycoside derivatives | NIPPON FINE CHEMICAL CO., LTD. (JP) | 1988-04-06 | — | — | EP | disclosed |