Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240057 | 0.85 | MEN1 (0.52) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL1252690 | 0.83 | MEN1 (0.50) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL17183627 | 0.83 | MEN1 (0.44) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL5372658 | 0.81 | MEN1 (0.49) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL546951 | 0.80 | MEN1 (0.47) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL28822328 | 0.79 | MEN1 (0.46) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL28767639 | 0.77 | KMT2A (0.45) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL23300514 | 0.76 | MAPT (0.44) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL3129414 | 0.75 | MEN1 (0.46) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL20240548 | 0.75 | MAOA (0.40) | MEN1KMT2AMAPTALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4859697-A | Substituted acenaphthenes and their use as inhibitors of phospholipase A2 | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-08-22 | — | — | US | disclosed |
| US-4806671-A | Substituted acenaphthenes and their use as inhibitors of phospholipase A2 | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-21 | — | — | US | disclosed |