Dexfosfoserine

Dexfosfoserine

SCHEMBL10496255

NC(COP(=O)(O)O)C(=O)O.[KH]

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 1/20 0.57
PGK2 P07205 1/20 0.57
PGD P52209 2/20 0.53
S1PR2 O95136 3/20 0.46
S1PR1 P21453 3/20 0.46
S1PR3 Q99500 3/20 0.46
S1PR5 Q9H228 2/20 0.46
P2RY10 O00398 6/20 0.42
GPR174 Q9BXC1 3/20 0.42
GPR34 Q9UPC5 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dexfosfoserine SCHEMBL6847 0.98 PGK1 (0.59) PGK1PGK2PGDS1PR2S1PR1
Dexfosfoserine SCHEMBL6846 0.98 PGK1 (0.59) PGK1PGK2PGDS1PR2S1PR1
Dexfosfoserine SCHEMBL20798048 0.98 PGK1 (0.59) PGK1PGK2PGDS1PR2S1PR1
Dexfosfoserine SCHEMBL29427835 0.98 PGK1 (0.59) PGK1PGK2PGDS1PR2S1PR1
Dexfosfoserine SCHEMBL5654871 0.96 PGK1 (0.57) PGK1PGK2PGDS1PR2S1PR1
Dexfosfoserine SCHEMBL4285878 0.96 PGK1 (0.57) PGK1PGK2PGDS1PR2S1PR1
Dexfosfoserine SCHEMBL4285884 0.96 PGK1 (0.57) PGK1PGK2PGDS1PR2S1PR1
Dexfosfoserine SCHEMBL28108476 0.96 PGK1 (0.57) PGK1PGK2PGDS1PR2S1PR1
Dexfosfoserine SCHEMBL28140769 0.96 PGK1 (0.57) PGK1PGK2PGDS1PR2S1PR1
Dexfosfoserine SCHEMBL27821486 0.96 PGK1 (0.57) PGK1PGK2PGDS1PR2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4883786-A CARDIOTROPIC AGENTS MAGIS FARMACEUTICI SRL (IT) 1989-11-28 US disclosed
EP-0167115-B1 NEW DERIVATIVES OF L-CARNITINE MAGIS FARMACEUTICI S.P.A. (IT) 1988-04-20 EP disclosed
EP-0167115-A2 New derivatives of L-carnitine MAGIS FARMACEUTICI S.P.A. (IT) 1986-01-08 EP disclosed