Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.42 |
| ▸ | GGH | Q92820 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 5/20 | 0.34 |
| ▸ | LAP3 | P28838 | 2/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.30 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20798046 | 0.98 | TGFBR1 (0.43) | TGFBR1GGHCA2CA4CA1 | |
| SCHEMBL6845 | 0.98 | TGFBR1 (0.43) | TGFBR1GGHCA2CA4CA1 | |
| SCHEMBL6848 | 0.98 | TGFBR1 (0.43) | TGFBR1GGHCA2CA4CA1 | |
| Calcium SCHEMBL5654876 | 0.95 | TGFBR1 (0.42) | TGFBR1GGHCA2CA4CA1 | |
| SCHEMBL13720890 | 0.95 | TGFBR1 (0.42) | TGFBR1GGHCA2CA4CA1 | |
| SCHEMBL13720886 | 0.95 | TGFBR1 (0.42) | TGFBR1GGHCA2CA4CA1 | |
| SCHEMBL13720237 | 0.95 | TGFBR1 (0.42) | TGFBR1GGHCA2CA4CA1 | |
| SCHEMBL13720235 | 0.95 | TGFBR1 (0.42) | TGFBR1GGHCA2CA4CA1 | |
| SCHEMBL5654860 | 0.95 | TGFBR1 (0.42) | TGFBR1GGHCA2CA4CA1 | |
| SCHEMBL10496242 | 0.95 | TGFBR1 (0.42) | TGFBR1GGHCA2CA4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4883786-A | CARDIOTROPIC AGENTS | MAGIS FARMACEUTICI SRL (IT) | 1989-11-28 | — | — | US | disclosed |
| EP-0167115-B1 | NEW DERIVATIVES OF L-CARNITINE | MAGIS FARMACEUTICI S.P.A. (IT) | 1988-04-20 | — | — | EP | disclosed |
| EP-0167115-A2 | New derivatives of L-carnitine | MAGIS FARMACEUTICI S.P.A. (IT) | 1986-01-08 | — | — | EP | disclosed |