Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SQLE | Q14534 | 2/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10496345 | 1.00 | NPSR1 (0.47) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL29991192 | 0.88 | NPSR1 (0.50) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL29053128 | 0.88 | NPSR1 (0.50) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL1195033 | 0.88 | NPSR1 (0.50) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL1195036 | 0.88 | NPSR1 (0.50) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL1759245 | 0.86 | NPSR1 (0.48) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL15482652 | 0.86 | NPSR1 (0.48) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL1759243 | 0.86 | NPSR1 (0.48) | NPSR1HCAR2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL2954948 | 0.85 | NPSR1 (0.47) | NPSR1HCAR2ALDH1A1HSD17B10ALOX15 | |
| SCHEMBL2953940 | 0.85 | NPSR1 (0.47) | NPSR1HCAR2ALDH1A1HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4818441-A | MEMBRANE STABILIZERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-04 | — | — | US | disclosed |