SCHEMBL2953940

SCHEMBL2953940

CCCCCC(C)=CC(=O)OCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.47
FAAH O00519 2/20 0.45
DGKA P23743 1/20 0.42
CES2 O00748 4/20 0.41
CES1 P23141 4/20 0.41
TSHR P16473 4/20 0.41
AKR1B1 P15121 1/20 0.40
HCAR2 Q8TDS4 1/20 0.39
ATM Q13315 1/20 0.39
PAM P19021 2/20 0.39
PPARG P37231 4/20 0.39
PPARD Q03181 4/20 0.39
PPARA Q07869 4/20 0.39
GPR84 Q9NQS5 3/20 0.39
HDAC11 Q96DB2 3/20 0.39
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
SLC22A6 Q4U2R8 1/20 0.39
SLC22A8 Q8TCC7 1/20 0.39
TLR2 O60603 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2954948 1.00 NPSR1 (0.47) NPSR1FAAHDGKACES2CES1
SCHEMBL15375163 1.00 NPSR1 (0.47) NPSR1FAAHDGKACES2CES1
SCHEMBL3360702 0.98 FAAH (0.47) NPSR1FAAHDGKACES2CES1
SCHEMBL15482689 0.98 FAAH (0.47) NPSR1FAAHDGKACES2CES1
SCHEMBL2838004 0.98 FAAH (0.47) NPSR1FAAHDGKACES2CES1
SCHEMBL13468257 0.98 FAAH (0.47) NPSR1FAAHDGKACES2CES1
SCHEMBL6524315 0.98 FAAH (0.47) NPSR1FAAHDGKACES2CES1
SCHEMBL7709678 0.98 FAAH (0.47) NPSR1FAAHDGKACES2CES1
SCHEMBL13129941 0.98 FAAH (0.47) NPSR1FAAHDGKACES2CES1
SCHEMBL7709682 0.98 FAAH (0.47) NPSR1FAAHDGKACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100254927-A1 OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS MONELL CHEMICAL SENSES CENTER (US) 2010-10-07 US claimed
EP-1474095-A4 OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS MONELL CHEMICAL SENSES CENTRE (US) 2007-11-28 EP claimed
US-20070020210-A1 Methods of reducing the perception of body odors with olfactory adaptation and cross-adapting agents MONELL CHEMICAL SENSES CENTER 2007-01-25 US claimed
EP-1474095-A1 OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS MONELL CHEMICAL SENSES CENTER (US) 2004-11-10 EP claimed
US-20030152538-A1 Olfactory adaptation and cross-adapting agents to reduce the perception of body odors SYMRISE INC. 2003-08-14 US claimed
WO-2003061609-A1 OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS MONELL CHEMICAL SENSES CENTER (US) 2003-07-31 WO claimed
CN-113710687-A Cyclopeptide antibiotics 豪夫迈·罗氏有限公司 2021-11-26 CN disclosed
US-20210009922-A1 METHODS AND COMPOSITIONS FOR REDUCING PERSISTENT ODOR IN CLOTHING AND MITIGATING BIOFILMS WELLS FARGO BANK, N.A. 2021-01-14 US disclosed
CN-111148739-A Cyclopeptide antibiotics 豪夫迈·罗氏有限公司 2020-05-12 CN disclosed
EP-1474095-B2 OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS MONELL CHEMICAL SENSES CENTRE (US) 2016-12-21 EP disclosed
EP-3089730-A1 DEODORANT COMPOSITIONS HAVING ANTIBACTERIAL AND ODOR BLOCKING PROPERTIES AND RELATED METHODS The Dial Corporation (US) 2016-11-09 EP disclosed
US-9381142-B2 Olfactory adaptation and cross-adapting agents to reduce the perception of body odors MONELL CHEMICAL SENSES CENTER (US) 2016-07-05 US disclosed
WO-2015102915-A1 DEODORANT COMPOSITIONS HAVING ANTIBACTERIAL AND ODOR BLOCKING PROPERTIES AND RELATED METHODS THE DIAL CORPORATION (US) 2015-07-09 WO disclosed
US-20100035948-A1 Furanone compounds and lactam analogues thereof UNILEVER PLC (GB) 2010-02-11 US disclosed
WO-2008040097-A1 FURANONE COMPOUNDS AND LACTAM ANALOGUES THEREOF BIOSIGNAL LIMITED (AU) 2008-04-10 WO disclosed
EP-1474095-A4 OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS MONELL CHEMICAL SENSES CENTRE (US) 2007-11-28 EP disclosed
US-20070020210-A1 Methods of reducing the perception of body odors with olfactory adaptation and cross-adapting agents MONELL CHEMICAL SENSES CENTER 2007-01-25 US disclosed
EP-1474095-A1 OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS MONELL CHEMICAL SENSES CENTER (US) 2004-11-10 EP disclosed
US-20030152538-A1 Olfactory adaptation and cross-adapting agents to reduce the perception of body odors SYMRISE INC. 2003-08-14 US disclosed
WO-2003061609-A1 OLFACTORY ADAPTATION AND CROSS-ADAPTING AGENTS TO REDUCE THE PERCEPTION OF BODY ODORS MONELL CHEMICAL SENSES CENTER (US) 2003-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035948-A1 Furanone compounds and lactam analogues thereof FDPS, CYP2C19, MRPL21 NPSR1 3097/4885FAAH 908/4885DGKA 4436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.