Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.56 |
| ▸ | PNP | P00491 | 5/20 | 0.54 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | HPRT1 | P00492 | 6/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508362 | 0.99 | TK1 (0.55) | TK1PNPSTING1PDE3BPDE3A | |
| SCHEMBL29503314 | 0.82 | PNP (0.56) | TK1PNPSTING1PDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL17186260 | 0.82 | PNP (0.62) | TK1PNPHPRT1USP2TSHR | |
| Hydrochloric Acid SCHEMBL17186500 | 0.81 | PNP (0.61) | TK1PNPHPRT1USP2TSHR | |
| SCHEMBL29286376 | 0.77 | TK1 (0.76) | TK1PNPHPRT1USP2TSHR | |
| SCHEMBL350397 | 0.75 | TK1 (0.82) | TK1PNPHPRT1USP2TSHR | |
| SCHEMBL6273292 | 0.74 | TK1 (0.55) | TK1PNPHPRT1USP2TSHR | |
| SCHEMBL9806969 | 0.74 | TK1 (0.71) | TK1PNPHPRT1USP2TSHR | |
| SCHEMBL6270960 | 0.73 | HPRT1 (0.66) | TK1PNPHPRT1USP2TSHR | |
| SCHEMBL8447170 | 0.73 | HPRT1 (0.62) | TK1PNPHPRT1USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845084-A | HERPES VIRUSES, AIDS | MERCK & CO., INC. (US) | 1989-07-04 | — | — | US | disclosed |
| EP-0152316-A1 | Substituted butyl guanines and their utilization in antiviral compositions | MERCK & CO. INC. (US) | 1985-08-21 | — | — | EP | disclosed |