SCHEMBL1049697

SCHEMBL1049697

BrC(=C(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.41
CES2 O00748 2/20 0.41
TSHR P16473 2/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
ALDH1A1 P00352 1/20 0.41
ESR1 P03372 1/20 0.39
PTPN1 P18031 1/20 0.39
GSK3B P49841 1/20 0.39
F2 P00734 2/20 0.38
CYP3A4 P08684 2/20 0.38
MAPT P10636 2/20 0.38
BLM P54132 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
F10 P00742 1/20 0.38
F12 P00748 1/20 0.38
F7 P08709 1/20 0.38
F3 P13726 1/20 0.38
PKM P14618 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL5051760 0.97 CES1 (0.39) CES1CES2TSHRDAONAPRT
SCHEMBL9859914 0.86 NPC1 (0.41) CES1CES2ESR1PTPN1TDP1
SCHEMBL24350341 0.86 NPC1 (0.41) CES1CES2ESR1PTPN1TDP1
SCHEMBL297692 0.84 CES1 (0.47) CES1CES2TSHRDAONAPRT
SCHEMBL5968341 0.84 CES1 (0.47) CES1CES2TSHRDAONAPRT
Broparestrol SCHEMBL29375131 0.81 ALDH1A1 (0.48) CES1CES2ALDH1A1ESR1PTGS2
Broparestrol SCHEMBL146181 0.81 ALDH1A1 (0.48) CES1CES2ALDH1A1ESR1PTGS2
SCHEMBL9579654 0.79 CES1 (0.43) CES1CES2TSHRDAONAPRT
SCHEMBL361224 0.79 F2 (0.43) CES1CES2TSHRDAONAPRT
SCHEMBL15835872 0.79 CES1 (0.43) CES1CES2TSHRDAONAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 308 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036717-A Near-infrared AIE fluorescent probe and preparation method and application thereof 徐州医科大学 2026-05-15 CN claimed
CN-119899133-A Temperature response fluorescent nanomaterial and preparation method and application thereof 常州大学 2025-04-29 CN claimed
CN-119060246-A Polymer-based pressure response label paper and preparation method thereof 东莞当纳利印刷有限公司 2024-12-03 CN claimed
CN-118290240-A Temperature stimulus responsive supermolecule cascading light capturing system and preparation method and application thereof 常州大学 2024-07-05 CN claimed
CN-118255785-A Chiral AIEgens of cinchona alkaloid amide skeleton, preparation method and application 宝鸡文理学院 2024-06-28 CN claimed
CN-118206417-A Cobalt catalytic dehalogenation deuteration method 中国科学院大连化学物理研究所 2024-06-18 CN claimed
CN-115819433-B Fluorescent compound containing tetraphenyl ethylene unit, preparation method and application thereof in microplastic dyeing tracing detection 北京师范大学 2024-06-07 CN claimed
CN-116375726-B Tetrastyryl cyclizing compound with photochromic and mechanochromatic properties and synthetic method and application thereof 华南师范大学 2024-05-14 CN claimed
CN-116462620-B Heavy metal high-selectivity probe and preparation method and application thereof 衡阳师范学院 2024-04-30 CN claimed
CN-116041225-B AIE fluorescent compound targeted by prostate specific membrane antigen and preparation method thereof 杭州思诺达医药科技有限责任公司 2024-03-29 CN claimed
CN-109776483-A Tetraphenyl ethylene macrocyclic compound and synthetic method and purposes with power cause fluorescence discoloration 华南师范大学 2019-05-21 CN claimed
CN-109337508-A A kind of preparation method of marine anti-pollution anticorrosive paint 海南大学 2019-02-15 CN claimed
CN-108440368-B A kind of fluorescence probe and its preparation method and application with AIE effect 广东工业大学 2019-01-22 CN claimed
CN-109134382-A phenanthroimidazole derivative with ESIPT and AIE properties and preparation method and application thereof 浙江工业大学 2019-01-04 CN claimed
CN-107056651-B A kind of tetraphenyl ethylene-diaminomaleonitrile derivative and preparation method thereof, application 广东工业大学 2018-10-30 CN claimed
CN-108530258-A Tetraphenyl ethylene class blue-fluorescence organic compound, preparation method and blue organic electroluminescent device 广东工业大学 2018-09-14 CN claimed
CN-108440368-A A kind of fluorescence probe and its preparation method and application with AIE effects 广东工业大学 2018-08-24 CN claimed
CN-108088825-A A kind of fluorescent chemicals and its synthetic method for formaldehyde examination and the application in Ratio-type fluorescent test paper 华南理工大学 2018-05-29 CN claimed
CN-107056651-A A kind of tetraphenyl ethylene diaminomaleonitrile derivative and preparation method thereof, application 广东工业大学 2017-08-18 CN claimed
CN-104004510-A Organic luminescent material simultaneously having piezoluminescence and aggregation-induced luminescence properties, and synthesis method and application thereof UNIV SUN YAT SEN 2014-08-27 CN claimed