Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 11/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 9/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497387 | 0.98 | CNR2 (0.42) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10498379 | 0.97 | THRA (0.41) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497914 | 0.95 | CNR2 (0.42) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL9341843 | 0.93 | CNR2 (0.42) | THRATHRBCYP1A2AKR1C3MEN1 | |
| SCHEMBL9342557 | 0.93 | CNR2 (0.42) | THRATHRBCYP1A2AKR1C3MEN1 | |
| SCHEMBL9342657 | 0.93 | CNR2 (0.42) | THRATHRBCYP1A2AKR1C3MEN1 | |
| SCHEMBL9342583 | 0.93 | CNR2 (0.42) | THRATHRBCYP1A2AKR1C3MEN1 | |
| SCHEMBL9342613 | 0.93 | CNR2 (0.42) | THRATHRBCYP1A2AKR1C3MEN1 | |
| SCHEMBL9339904 | 0.93 | CNR2 (0.42) | THRATHRBCYP1A2AKR1C3MEN1 | |
| SCHEMBL9337979 | 0.93 | CNR2 (0.42) | THRATHRBCYP1A2AKR1C3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |