Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497412 | 0.87 | MAPT (0.65) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL10497489 | 0.87 | MAPT (0.65) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL14668178 | 0.78 | MAPT (0.43) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL10497819 | 0.78 | TYR (0.62) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL5580044 | 0.77 | TYR (0.52) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL5580045 | 0.77 | TYR (0.52) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL10498227 | 0.75 | PIM1 (0.47) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL10497466 | 0.75 | MEN1 (0.61) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL4067532 | 0.75 | MAPT (0.48) | MAPTMEN1KMT2ANPC1PIM1 | |
| SCHEMBL30301081 | 0.75 | MAPT (0.48) | MAPTMEN1KMT2ANPC1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | claimed |