Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5580044 | 1.00 | TYR (0.52) | TYRCHEK1DAPK3PRKD3PIM1 | |
| SCHEMBL10497609 | 0.77 | MAPT (0.55) | PIM1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4067532 | 0.72 | MAPT (0.48) | PIM1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL30301081 | 0.72 | MAPT (0.48) | PIM1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL5904503 | 0.72 | MAPT (0.48) | PIM1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL30336864 | 0.72 | MAPT (0.48) | PIM1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL11371014 | 0.72 | MAPT (0.61) | TYRMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14521148 | 0.72 | PLK4 (0.61) | CHEK1PRKD3CSNK1A1CDK8CLK4 | |
| SCHEMBL13390288 | 0.69 | DVL1 (0.53) | TYRMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14145614 | 0.67 | MAPT (0.55) | TYRMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |