Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.52 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497961 | 0.99 | ABCG2 (0.51) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL10497947 | 0.99 | ABCG2 (0.51) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL10497651 | 0.99 | ABCG2 (0.51) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL10497605 | 0.96 | ABCG2 (0.51) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL10497147 | 0.96 | ABCG2 (0.51) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL10497674 | 0.96 | ABCG2 (0.51) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL9337688 | 0.94 | ABCG2 (0.51) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL9342405 | 0.94 | ABCG2 (0.51) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL10498782 | 0.94 | MAOB (0.52) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL9337816 | 0.94 | ABCG2 (0.51) | MEN1USP2ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |