Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10498083 | 0.94 | MEN1 (0.52) | MAOBABCG2KMT2ASMN1; SMN2LMNA | |
| SCHEMBL10497947 | 0.93 | ABCG2 (0.51) | ABCG2KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL10497651 | 0.93 | ABCG2 (0.51) | ABCG2KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL10497961 | 0.93 | ABCG2 (0.51) | ABCG2KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL10497147 | 0.90 | ABCG2 (0.51) | ABCG2KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL10497674 | 0.90 | ABCG2 (0.51) | ABCG2KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL10497605 | 0.90 | ABCG2 (0.51) | ABCG2KMT2ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL9338572 | 0.90 | MAOB (0.56) | MAOBABCG2MAPTRAB9AKMT2A | |
| SCHEMBL10497709 | 0.90 | THRA (0.52) | KMT2AMEN1 | |
| SCHEMBL10497532 | 0.90 | THRA (0.52) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |