Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 5/20 | 0.51 |
| ▸ | THRB | P10828 | 5/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 12/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 11/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497336 | 0.91 | THRA (0.48) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10498796 | 0.89 | THRA (0.46) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10498045 | 0.87 | PLK1 (0.54) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497951 | 0.86 | PLK1 (0.53) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497293 | 0.85 | THRA (0.52) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10498806 | 0.84 | THRA (0.51) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497461 | 0.83 | THRA (0.54) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL25207853 | 0.83 | KAT8 (0.57) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10498355 | 0.83 | THRA (0.64) | THRATHRBATG4BPLA2G1BCYP1A2 | |
| SCHEMBL10497557 | 0.83 | KAT8 (0.57) | THRATHRBATG4BPLA2G1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |