Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499733 | 0.86 | MEN1 (0.65) | MEN1USP2KMT2AL3MBTL1GRM2 | |
| SCHEMBL10498575 | 0.86 | MEN1 (0.72) | MEN1USP2KMT2AL3MBTL1KDM4E | |
| SCHEMBL10498946 | 0.85 | MEN1 (0.74) | MEN1USP2KMT2AL3MBTL1GRM2 | |
| SCHEMBL9685827 | 0.84 | SLC6A9 (0.54) | MEN1USP2KMT2AL3MBTL1GRM2 | |
| SCHEMBL10498998 | 0.82 | MEN1 (0.66) | MEN1USP2KMT2AL3MBTL1KDM4E | |
| SCHEMBL10499016 | 0.82 | MEN1 (0.63) | MEN1USP2KMT2AL3MBTL1GRM2 | |
| SCHEMBL10925730 | 0.82 | — | — | |
| Fumaric Acid SCHEMBL10498627 | 0.79 | MEN1 (0.62) | MEN1USP2KMT2AL3MBTL1GRM2 | |
| Fumaric Acid SCHEMBL10498622 | 0.79 | MEN1 (0.62) | MEN1USP2KMT2AL3MBTL1GRM2 | |
| SCHEMBL10498885 | 0.79 | MEN1 (0.61) | MEN1USP2KMT2AL3MBTL1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123962-B1 | BENZIMIDAZOLE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION | KANEBO, LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |
| US-4603130-A | ANTIHISTAMINES | KANEBO, LTD. (JP) | 1986-07-29 | — | — | US | disclosed |
| EP-0123962-A2 | Benzimidazole derivative, process for the preparation thereof and pharmaceutical composition | KANEBO, LTD. (JP) | 1984-11-07 | — | — | EP | disclosed |