SCHEMBL10499112

SCHEMBL10499112

CCCCCCCCC=CCCCCCCCC(=O)Oc1ccccc1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLM Q9NP87 2/20 0.61
POLK Q9UBT6 2/20 0.61
POLL Q9UGP5 2/20 0.61
POLH Q9Y253 2/20 0.61
HTR2A P28223 2/20 0.51
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 1/20 0.50
RECQL P46063 1/20 0.50
KMT2A Q03164 1/20 0.50
ELANE P08246 1/20 0.50
SOAT2 O75908 1/20 0.50
SOAT1 P35610 1/20 0.50
FAAH O00519 2/20 0.48
EPHX2 P34913 2/20 0.48
PPARG P37231 3/20 0.47
DGKA P23743 1/20 0.47
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46
ALDH1A1 P00352 4/20 0.46
F7 P08709 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10499098 1.00 POLM (0.61) POLMPOLKPOLLPOLHHTR2A
SCHEMBL8088316 0.92 KMT2A (0.57) POLMPOLKPOLLPOLHKDM4E
SCHEMBL27508353 0.92 KMT2A (0.57) POLMPOLKPOLLPOLHKDM4E
SCHEMBL9322247 0.92 KMT2A (0.57) POLMPOLKPOLLPOLHKDM4E
SCHEMBL30666136 0.90 POLM (0.67) POLMPOLKPOLLPOLHHTR2A
SCHEMBL8676312 0.90 KDM4E (0.59) POLMPOLKPOLLPOLHKDM4E
SCHEMBL5706039 0.86 MEN1 (0.65) POLMPOLKPOLLPOLHKDM4E
SCHEMBL20739827 0.85 POLM (0.62) POLMPOLKPOLLPOLHHTR2A
SCHEMBL22261900 0.85 POLM (0.62) POLMPOLKPOLLPOLHHTR2A
SCHEMBL26090058 0.85 POLM (0.62) POLMPOLKPOLLPOLHHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4835312-A Production process of N-substituted amide compounds MITSUI CHEMICALS, INCORPORATED (JP) 1989-05-30 US disclosed