Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLM | Q9NP87 | 2/20 | 0.62 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.62 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.62 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.62 |
| ▸ | TOP2A | P11388 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26090058 | 1.00 | POLM (0.62) | POLMPOLKPOLLPOLHTOP2A | |
| SCHEMBL30666136 | 0.94 | POLM (0.67) | POLMPOLKPOLLPOLHEPHX2 | |
| SCHEMBL4083842 | 0.92 | MEN1 (0.59) | POLMPOLKPOLLPOLHTOP2A | |
| SCHEMBL4089868 | 0.92 | MEN1 (0.59) | POLMPOLKPOLLPOLHTOP2A | |
| SCHEMBL22975372 | 0.92 | MEN1 (0.59) | POLMPOLKPOLLPOLHTOP2A | |
| SCHEMBL4083649 | 0.92 | MEN1 (0.59) | POLMPOLKPOLLPOLHTOP2A | |
| SCHEMBL9186714 | 0.92 | MEN1 (0.59) | POLMPOLKPOLLPOLHTOP2A | |
| SCHEMBL4090350 | 0.90 | MEN1 (0.60) | POLMPOLKPOLLPOLHTOP2A | |
| SCHEMBL9670150 | 0.89 | MEN1 (0.50) | POLMPOLKPOLLPOLHTOP2A | |
| SCHEMBL26090061 | 0.87 | POLM (0.51) | POLMPOLKPOLLPOLHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019030643-A1 | COMPOSITIONS OF EUGENOL DERIVATIVES FOR TREATMENT OF VISCERAL LEISHMANIASIS | FOUNDATION FOR NEGLECTED DISEASE RESEARCH (IN) | 2019-02-14 | — | — | WO | disclosed |