Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | GLA | P06280 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | HTR3A | P46098 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22158321 | 0.98 | MAPT (0.65) | MAPTALDH1A1GLAHPGDACHE | |
| Potassium SCHEMBL10499155 | 0.96 | MAPT (0.62) | MAPTALDH1A1GLAHPGDACHE | |
| SCHEMBL28184246 | 0.87 | BACE1 (0.60) | MAPTALDH1A1GLAHPGDACHE | |
| SCHEMBL7913572 | 0.85 | MAPT (0.65) | MAPTALDH1A1GLAHPGDACHE | |
| SCHEMBL29077372 | 0.83 | BACE1 (0.61) | MAPTALDH1A1GLAHPGDACHE | |
| Acridine SCHEMBL28059305 | 0.82 | ALDH1A1 (0.94) | MAPTALDH1A1GLAHPGDACHE | |
| Acridine SCHEMBL28143558 | 0.82 | ALDH1A1 (0.94) | MAPTALDH1A1GLAHPGDACHE | |
| Acridine SCHEMBL3045498 | 0.79 | ALDH1A1 (1.00) | MAPTALDH1A1GLAHPGDACHE | |
| Acridine SCHEMBL8339 | 0.79 | ALDH1A1 (1.00) | MAPTALDH1A1GLAHPGDACHE | |
| Acridine SCHEMBL1772714 | 0.79 | ALDH1A1 (1.00) | MAPTALDH1A1GLAHPGDACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |