Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1685878 | 1.00 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL7181519 | 0.96 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL7171227 | 0.96 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL7173393 | 0.96 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL6913575 | 0.96 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL7178276 | 0.96 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL7174711 | 0.96 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL7172321 | 0.96 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL7178932 | 0.96 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL29753982 | 0.96 | GRIN2D (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177956-A1 | METAL BIS(IMINO) ARYL COMPOUNDS AND METHODS THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| US-20230250200-A1 | IMPROVED CATALYSTS FOR INTERMOLECULAR CYCLOADDITION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2023-08-10 | — | — | US | disclosed |
| EP-3058002-B1 | POLYETHYLENE OF RAISED TEMPERATURE RESISTANCE | BASELL POLYOLEFINE GMBH (DE) | 2019-08-21 | — | — | EP | disclosed |
| EP-1943281-B1 | HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE | BASELL POLYOLEFINE GMBH (DE) | 2017-09-20 | — | — | EP | disclosed |
| US-9671047-B2 | Polyethylene of raised temperature resistance | BASELL POLYOLEFINE GMBH (DE) | 2017-06-06 | — | — | US | disclosed |
| EP-2328968-B1 | POLYETHYLENE FOR INJECTION MOLDINGS | BASELL POLYOLEFINE GMBH (DE) | 2017-05-03 | — | — | EP | disclosed |
| US-20160298795-A1 | POLYETHYLENE OF RAISED TEMPERATURE RESISTANCE | BASELL POLYOLEFINE GMBH (DE) | 2016-10-13 | — | — | US | disclosed |
| US-9090761-B2 | Polyethylene for injection moldings | BASELL POLYOLEFINE GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| EP-1971577-B1 | Process for the preparation of unsymmetric bis(imino) compounds | BASELL POLYOLEFINE GMBH (DE) | 2014-11-26 | — | — | EP | disclosed |
| US-8404792-B2 | Cyclobutene polymers and methods of making the same | North Carolina Sate University (US) | 2013-03-26 | — | — | US | disclosed |
| EP-1753794-B1 | POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION | BASELL POLYOLEFINE GMBH (DE) | 2008-06-04 | — | — | EP | disclosed |
| US-20070255033-A1 | Polyethylene for Injection Moldings | BASELL POYOLEFINE GMBH (DE) | 2007-11-01 | — | — | US | disclosed |
| US-20070213205-A1 | Polyethylene and Catalyst Composition for its Preparation | BASELL POLYOLEFINE GMBH (DE) | 2007-09-13 | — | — | US | disclosed |
| US-7202316-B2 | Modified particle, catalyst component for addition polymerization, catalyst for addition polymerization and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-10 | — | — | US | disclosed |
| US-20050192178-A1 | Modified particle, catalyst component for addition polymerization, catalyst for addition polymerization and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-09-01 | — | — | US | disclosed |
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |
| US-6656867-B2 | Coordination catalyst | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-12-02 | — | — | US | disclosed |
| US-20030119662-A1 | Transition metal catalysts for diene polymerizations | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-06-26 | — | — | US | disclosed |
| US-6479601-B1 | Transition metal catalysts for diene polymerizations | THE GOODYEAR TIRE & RUBBER COMPANY | 2002-11-12 | — | — | US | disclosed |
| EP-1059313-A1 | Transition metal catalyst component for polymerization, aromatic vinyl compound-olefin copolymer and process for its production by means of the catalyst component | DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-12-13 | — | — | EP | disclosed |