Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GRK2 | P25098 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268396 | 0.87 | POLB (0.58) | HSD17B10NPC1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL30944763 | 0.87 | POLB (0.58) | HSD17B10NPC1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL17293747 | 0.87 | POLB (0.58) | HSD17B10NPC1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL6274364 | 0.87 | POLB (0.58) | HSD17B10NPC1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL6267767 | 0.85 | POLB (0.59) | HSD17B10NPC1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL10499999 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HDAC4HDAC3HDAC1HDAC2 | |
| SCHEMBL6273868 | 0.81 | POLB (0.61) | HSD17B10NPC1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL8130639 | 0.80 | TP53 (0.59) | NPC1ALDH1A1HDAC4HDAC3HDAC1 | |
| SCHEMBL1289613 | 0.79 | CHRM2 (0.50) | HSD17B10NPC1CHRM2ALDH1A1POLB | |
| SCHEMBL30293244 | 0.79 | CHRM2 (0.50) | HSD17B10NPC1CHRM2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835180-A | N-(ω-cyanoalkyl)aminophenols and use as inhibitors of lipoxygenase activity | STERLING DRUG INC. (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0262618-A2 | N-(omega)-cyanoalkyl)aminophenols, and their preparation | STERLING DRUG INC. (US) | 1988-04-06 | — | — | EP | disclosed |