Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15637612 | 0.83 | GSR (0.47) | MAOBHDAC1HDAC8HDAC6GSR | |
| SCHEMBL11815004 | 0.80 | MAPT (0.59) | MAOBMAPTNPC1RAB9ALMNA | |
| SCHEMBL3807035 | 0.80 | ALDH1A1 (0.45) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL434269 | 0.80 | MAPT (0.59) | MAOBMAPTNPC1RAB9ALMNA | |
| SCHEMBL10500469 | 0.79 | GSR (0.58) | MAOBHDAC1HDAC8HDAC6GSR | |
| SCHEMBL10500140 | 0.79 | MAPT (0.46) | MAOBHDAC1HDAC8HDAC6GSR | |
| SCHEMBL11810985 | 0.77 | KDM4E (0.65) | MAOBMAPTKMT2ANPC1RAB9A | |
| SCHEMBL11810990 | 0.77 | KDM4E (0.65) | MAOBMAPTKMT2ANPC1RAB9A | |
| SCHEMBL11224681 | 0.77 | MAPT (0.58) | MAOBMAPTKMT2ANPC1RAB9A | |
| SCHEMBL27880439 | 0.77 | GSR (0.55) | MAOBHDAC1HDAC8HDAC6GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835312-A | Production process of N-substituted amide compounds | MITSUI CHEMICALS, INCORPORATED (JP) | 1989-05-30 | — | — | US | disclosed |