Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10503537 | 0.87 | NPC1 (0.46) | ALDH1A1RAB9ANPC1SMN1; SMN2ABCB11 | |
| SCHEMBL9871694 | 0.87 | ALDH1A1 (0.38) | ALDH1A1RAB9ANPC1SMN1; SMN2ABCB11 | |
| SCHEMBL10502738 | 0.83 | ALDH1A1 (0.35) | ALDH1A1RAB9ANPC1SMN1; SMN2ABCB11 | |
| SCHEMBL10502233 | 0.83 | NPC1 (0.35) | ALDH1A1RAB9ANPC1SMN1; SMN2ABCB11 | |
| SCHEMBL10580258 | 0.82 | ALDH1A1 (0.35) | ALDH1A1RAB9ANPC1SMN1; SMN2ABCB11 | |
| SCHEMBL16790535 | 0.76 | NPC1 (0.36) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL18175531 | 0.76 | NPC1 (0.34) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL5984202 | 0.74 | FNTA (0.42) | SMN1; SMN2FNTAFNTBMEN1KMT2A | |
| SCHEMBL9872313 | 0.74 | NPC1 (0.50) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL9359437 | 0.73 | NR1H4 (0.33) | RAB9ANPC1SMN1; SMN2NR1H4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4868251-A | A BENZOTRIAZOLE COVALENTLY BONDED TO RESIN, CONTACT LENSES | ALLERGAN, INC. (US) | 1989-09-19 | — | — | US | disclosed |
| US-4845180-A | POLYURETHANES FOR CONTACT LENSES AND EYEGLASSES | ALLERGAN, INC. (US) | 1989-07-04 | — | — | US | disclosed |