Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 1/20 | 0.74 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.74 |
| ▸ | METAP2 | P50579 | 8/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10501010 | 0.89 | METAP2 (0.67) | MPIPHOSPHO1METAP2 | |
| SCHEMBL10501686 | 0.85 | MPI (1.00) | MPIPHOSPHO1METAP2 | |
| SCHEMBL10502440 | 0.83 | MPI (0.74) | MPIPHOSPHO1METAP2 | |
| SCHEMBL10501361 | 0.83 | MPI (0.51) | MPIPHOSPHO1METAP2 | |
| SCHEMBL10501672 | 0.82 | MPI (0.72) | MPIPHOSPHO1METAP2 | |
| SCHEMBL10502317 | 0.79 | MPI (0.67) | MPIPHOSPHO1METAP2 | |
| SCHEMBL10501879 | 0.77 | METAP2 (0.64) | MPIPHOSPHO1METAP2 | |
| SCHEMBL10501789 | 0.77 | METAP2 (0.71) | MPIPHOSPHO1METAP2 | |
| SCHEMBL10501423 | 0.77 | MPI (0.78) | MPIPHOSPHO1METAP2 | |
| SCHEMBL10501611 | 0.75 | METAP2 (0.66) | MPIPHOSPHO1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154851-B1 | BENZISOSELENAZOLETHIONES,PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS | A. Nattermann & Cie. GmbH (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-4711961-A | Benzisoselenazolethiones and process for the treatment of various diseases in humans | A. NATTERMANN & CIE GMBH (DE) | 1987-12-08 | — | — | US | disclosed |