SCHEMBL1050263 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	ACE	P12821	6/20	0.41

▸	ECE1	P42892	5/20	0.40

▸	ITGB2	P05107	1/20	0.39

▸	ICAM1	P05362	1/20	0.39

▸	ITGAL	P20701	1/20	0.39

▸	POLB	P06746	1/20	0.37

▸	GFER	P55789	1/20	0.37

▸	SDCBP	O00560	1/20	0.37

▸	SDC2	P34741	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL1052259	1.00	ACE (0.41)	ACEECE1ITGB2ICAM1ITGAL
SCHEMBL935379	1.00	ACE (0.41)	ACEECE1ITGB2ICAM1ITGAL
SCHEMBL935380	1.00	ACE (0.41)	ACEECE1ITGB2ICAM1ITGAL
SCHEMBL936102	0.90	ECE1 (0.46)	ACEECE1ITGB2ICAM1ITGAL
SCHEMBL936100	0.90	ECE1 (0.46)	ACEECE1ITGB2ICAM1ITGAL
SCHEMBL1055888	0.90	ECE1 (0.46)	ACEECE1ITGB2ICAM1ITGAL
SCHEMBL935339	0.89	GPR84 (0.41)	ECE1ITGB2ICAM1ITGALPOLB
SCHEMBL957431	0.89	GPR84 (0.41)	ECE1ITGB2ICAM1ITGALPOLB
SCHEMBL955533	0.89	GPR84 (0.41)	ECE1ITGB2ICAM1ITGALPOLB
SCHEMBL935823	0.89	ECE1 (0.45)	ACEECE1ITGB2ICAM1ITGAL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011010748-A1	INDOLE DERIVATIVE AND SALTINESS-STRENGTHENING AGENT CONTAINING THE DERIVATIVE	味の素株式会社 (JP)	2011-01-27	—	—	WO	disclosed