SCHEMBL105029

SCHEMBL105029

Clc1nc2ccccc2o1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.54
RAB9A P51151 7/20 0.54
MAPT P10636 4/20 0.54
PSMB8 P28062 1/20 0.50
TP53 P04637 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
LMNA P02545 1/20 0.48
ALDH1A1 P00352 4/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
HSD17B10 Q99714 3/20 0.47
PKM P14618 2/20 0.47
HPGD P15428 2/20 0.47
HCRTR1 O43613 1/20 0.47
GAA P10253 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
KDM4E B2RXH2 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10670777 0.98 NPC1 (0.52) NPC1RAB9AMAPTPSMB8TP53
SCHEMBL11221096 0.98 NPC1 (0.52) NPC1RAB9AMAPTPSMB8TP53
Ammonia Solution, Strong SCHEMBL28837681 0.98 NPC1 (0.52) NPC1RAB9AMAPTPSMB8TP53
SCHEMBL11044195 0.96 NPC1 (0.50) NPC1RAB9AMAPTPSMB8TP53
SCHEMBL6246047 0.88 NPC1 (0.44) NPC1RAB9AMAPTPSMB8TP53
SCHEMBL10599201 0.88 RAB9A (0.46) NPC1RAB9AMAPTSMN1; SMN2LMNA
Acetonitrile SCHEMBL5483189 0.88 PSMB8 (0.55) NPC1RAB9AMAPTPSMB8TP53
Formic Acid SCHEMBL28868401 0.88 MAPT (0.48) NPC1RAB9AMAPTPSMB8TP53
Oxazole SCHEMBL9110217 0.82 NPC1 (0.40) NPC1RAB9AMAPTPSMB8TP53
SCHEMBL29531707 0.77 NPC1 (0.69) NPC1RAB9AMAPTPSMB8TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2506 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260110689-A1 METHODS AND COMPOSITIONS RELATED TO MODIFIED FLUOROPHORES UNIV TEXAS (US) 2026-04-23 US claimed
CN-115124486-B Benzoxazole derivative and preparation method and application thereof 武汉理工大学 2024-07-23 CN claimed
CN-112625035-B 5-chlorobenzoxazole derivative or salt acceptable as pesticide, composition and application thereof 海利尔药业集团股份有限公司 2024-04-12 CN claimed
CN-117343054-A Fluorescent probe and fluorescent label for real-time nondestructive visual monitoring of freshness of meat products, and preparation method and application thereof 重庆医药高等专科学校 2024-01-05 CN claimed
CN-115449261-A Preparation method of coffee flavor printing ink based on coffee bean waste recovery 扬州市祥华新材料科技有限公司 2022-12-09 CN claimed
CN-114276340-B Chlorobenzoxazole derivative or pharmaceutically acceptable salt thereof and application thereof 郑州大学 2022-10-04 CN claimed
CN-115124486-A Benzoxazole derivative and preparation method and application thereof 武汉理工大学 2022-09-30 CN claimed
CN-114276340-A Chlorobenzoxazole derivative or pharmaceutically acceptable salt thereof and application thereof 郑州大学 2022-04-05 CN claimed
US-11161826-B2 Manufacturing methods and polymorphs of a thiazoline anti-hyperalgesic agent ACADIA PHARMACEUTICALS INC. (US) 2021-11-02 US claimed
CN-111138424-B Diamine monomer containing benzoxazole and carbazole structures and preparation method and application thereof 中山大学 2021-02-09 CN claimed
EP-0141053-B1 METHOD FOR THE PREPARATION OF 2-CHLORBENZOXAZOLES CASSELLA Aktiengesellschaft (DE) 1987-08-19 EP claimed
EP-0087701-B1 PROCESS FOR THE PREPARATION OF 2-CHLOROBENZOXAZOLS CASSELLA Aktiengesellschaft (DE) 1986-08-20 EP claimed
US-4517370-A Process for preparing 2-chlorobenzoxazoles CASSELLA AKTIENGESELLSCHAFT (DE) 1985-05-14 US claimed
EP-0087701-A2 Process for the preparation of 2-chlorobenzoxazols CASSELLA Aktiengesellschaft (DE) 1983-09-07 EP claimed
EP-0062254-A1 Substituted acetanilides, process for their preparation and their use as herbicides NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1982-10-13 EP claimed
WO-1982001554-A1 POLYCARBONATES STABILIZED BY HALOHYDROCARBON,HALOCARBON OR SILANE GROUPS MCALISTER ROY E 1982-05-13 WO claimed
EP-0027144-A4 POLYCARBONATES STABILIZED BY HALOHYDROCARBON, HALOCARBON OR SILANE GROUPS. MCALISTER ROY E 1981-05-19 EP claimed
EP-0027144-A1 POLYCARBONATES STABILIZED BY HALOHYDROCARBON, HALOCARBON OR SILANE GROUPS McALISTER, Roy Edward (US) 1981-04-22 EP claimed
US-4243779-A FLUORESCENCE, PHOTOSTABILITY MCALISTER ROY E 1981-01-06 US claimed
WO-1980002290-A1 POLYCARBONATES STABILIZED BY HALOHYDROCARBON,HALOCARBON OR SILANE GROUPS MCALISTER R 1980-10-30 WO claimed