Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 2/20 | 0.52 |
| ▸ | WDR5 | P61964 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.47 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 4/20 | 0.43 |
| ▸ | ATP4B | P51164 | 4/20 | 0.43 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.40 |
| ▸ | ENGASE | Q8NFI3 | 2/20 | 0.40 |
| ▸ | SARM1 | Q6SZW1 | 2/20 | 0.40 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.39 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.39 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.39 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.39 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.39 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.39 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.39 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10504119 | 0.90 | BRS3 (0.49) | BRS3WDR5KMT2ASHMT2AGXT | |
| SCHEMBL10503436 | 0.85 | MAPT (0.52) | BRS3WDR5KMT2ASHMT2AGXT | |
| SCHEMBL10503257 | 0.82 | BRS3 (0.48) | BRS3WDR5KMT2ASHMT2AGXT | |
| SCHEMBL10578851 | 0.78 | BRS3 (0.74) | BRS3WDR5KMT2ASHMT2CYP2C9 | |
| SCHEMBL10503421 | 0.78 | BRS3 (0.56) | BRS3WDR5KMT2ASHMT2AGXT | |
| SCHEMBL10503647 | 0.75 | KMT2A (0.47) | BRS3WDR5KMT2ASHMT2AGXT | |
| SCHEMBL10579864 | 0.74 | BRS3 (0.62) | BRS3WDR5KMT2ASHMT2ALDH1A1 | |
| SCHEMBL10504425 | 0.71 | WDR5 (0.45) | BRS3WDR5KMT2ASHMT2AGXT | |
| SCHEMBL27663985 | 0.71 | BRS3 (0.57) | BRS3WDR5KMT2ASHMT2AGXT | |
| SCHEMBL5669330 | 0.70 | BRS3 (0.58) | BRS3WDR5KMT2ASHMT2AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194458-B1 | NEW INDOLE DERIVATIVES, THE PRODUCTION AND USES THEREOF | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-06-14 | — | — | EP | disclosed |
| US-4743609-A | ANTIULCER | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-05-10 | — | — | US | disclosed |
| EP-0194458-A1 | New indole derivatives, the production and uses thereof | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-09-17 | — | — | EP | disclosed |