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Sugi Predict / Targets / WDR5

WDR5

WD repeat-containing protein 5 · P61964 · WDR5 on Sugi Atlas →

58,278 patent compounds predicted against WDR5, 28,471 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL282334 SCHEMBL282334 0.73 18/20
SCHEMBL330320 SCHEMBL330320 0.78 17/20
SCHEMBL560405 SCHEMBL560405 0.50 15/20
SCHEMBL561403 SCHEMBL561403 0.49 12/20
SCHEMBL219606 SCHEMBL219606 0.56 11/20
SCHEMBL560745 SCHEMBL560745 0.50 11/20
SCHEMBL44512 SCHEMBL44512 0.52 10/20
SCHEMBL44216 SCHEMBL44216 0.52 10/20
SCHEMBL44645 SCHEMBL44645 0.51 10/20
SCHEMBL44301 SCHEMBL44301 0.66 9/20
SCHEMBL44398 SCHEMBL44398 0.46 9/20
SCHEMBL113349 SCHEMBL113349 0.36 9/20
SCHEMBL282228 SCHEMBL282228 0.55 8/20
SCHEMBL408221 SCHEMBL408221 0.44 8/20
SCHEMBL108698 SCHEMBL108698 0.59 7/20
SCHEMBL283385 SCHEMBL283385 0.57 7/20
SCHEMBL398803 SCHEMBL398803 0.57 7/20
SCHEMBL463267 SCHEMBL463267 0.52 7/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL440262) 0.51 7/20
SCHEMBL560769 SCHEMBL560769 0.48 7/20

Clinical trials — most relevant to WDR5 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study PHASE3COMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Characterization of WAGR Syndrome and Other Chromosome 11 Gene Deletions nanCOMPLETED
Child Development and Genetic Biomarkers(II): Gene Verification and Data Integration nanUNKNOWN
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis nanCOMPLETED
Microarray Analysis in Syndromic Obesity nanCOMPLETED
MEHMO Natural History and Biomarkers nanRECRUITING
Mapping Novel Disease Genes for Dilated Cardiomyopathy nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome nanRECRUITING
Study of a Candidate Gene Involved in Goldenhar Syndrome. nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
PCD New Gene Discovery nanCOMPLETED
Molecular Diagnosis of Syndromic or Isolated Severe Intellectual Disability Using Whole Exome Sequencing : a Pilot Study nanCOMPLETED
Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks nanRECRUITING
Genetics of Primary Ciliary Dyskinesia nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Exome Sequencing Study in Cardiomyopathy to Identify New Risk Variants nanUNKNOWN
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Multidisciplinary Evaluation and a Genome-wide Analysis in a Cohort of Idiopathic Short Stature Patients nanRECRUITING
Natural History Study of GEMIN-5 Related Neurodevelopmental Disorder nanRECRUITING
Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity. nanRECRUITING
Genetic Study of Patients With Primary Ciliary Dyskinesia nanCOMPLETED
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science nanRECRUITING
A Patient-tailored Genetic/Biomarker/iPSC Combined Approach in ALS - PERMEALS nanRECRUITING
Identification of the Genetic Causes of Rare Diseases With Negative Exome Findings nanUNKNOWN
Better Delineation of DDX3X Related Phenotype and Epigenetic Signature. nanUNKNOWN
Genetic Analyses of Nonsyndromic and Syndromic Deafness in Pakistan nanENROLLING_BY_INVITATION
iPSC Neurons From Adult Survivors of Childhood Cancer Who Have Persistent Vincristine-Induced Neuropathy nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a WDR5 binder may also engage these)

ProteinNameSimilarity
Q498M4 — 1.000 Q498M4 →
P61965 — 1.000 P61965 →
Q5M786 — 1.000 Q5M786 →
Q2KIG2 — 1.000 Q2KIG2 →
Q6P3H7 — 0.934 Q6P3H7 →
Q5M7K4 — 0.932 Q5M7K4 →
Q9W7I5 — 0.932 Q9W7I5 →
Q3MHL3 — 0.932 Q3MHL3 →
Q5RF92 — 0.930 Q5RF92 →
O93377 — 0.930 O93377 →
Q9V3J8 — 0.929 Q9V3J8 →
Q6INH0 — 0.929 Q6INH0 →
RBBP4 Histone-binding protein RBBP4 0.928 landscape →
Q60972 — 0.928 Q60972 →
Q8BFQ4 — 0.916 Q8BFQ4 →
Q7ZTY4 — 0.915 Q7ZTY4 →
PRKG1 cGMP-dependent protein kinase 1 0.915 landscape →
P00516 — 0.915 P00516 →
WDR82 WD repeat-containing protein 82 0.913 landscape →
P0C605 — 0.913 P0C605 →
Q6P315 — 0.910 Q6P315 →
O77676 — 0.909 O77676 →
F1LTR1 — 0.908 F1LTR1 →
Q8AVH1 — 0.907 Q8AVH1 →
Q9QXE7 — 0.906 Q9QXE7 →
Q5ZMV7 — 0.906 Q5ZMV7 →
Q5SP67 — 0.904 Q5SP67 →
Q62639 — 0.903 Q62639 →
Q91854 — 0.902 Q91854 →
Q58E77 — 0.902 Q58E77 →