Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.64 |
| ▸ | CES2 | O00748 | 1/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27618558 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| Benzene SCHEMBL6698503 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| SCHEMBL43943 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| Benzene SCHEMBL11066939 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| Benzene SCHEMBL7058395 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| Benzene SCHEMBL2333780 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| Benzene SCHEMBL3421936 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| SCHEMBL9688483 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| SCHEMBL1331954 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| Benzene SCHEMBL9511700 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114128-B1 | 3-AMINO-2-OXO-AZETIDINE DERIVATIVES CONTAINING IN POSITION 1 A NITROGEN HETEROCYCLIC RADICAL, PROCESS FOR THEIR PREPARATION, THEIR USE AS THERAPEUTICAL AGENTS AND INTERMEDIATES FOR THEIR PREPARATION | ROUSSEL-UCLAF (FR) | 1989-03-22 | — | — | EP | disclosed |
| EP-0070588-B1 | METHOD OF PREPARING 1-ALPHA-HYDROXYVITAMIN D AND 1-ALPHA-HYDROXY-PREVITAMIN D COMPOUNDS, AND ADDUCT OF A PREVITAMIN D OR TACHYSTEROL COMPOUND WITH A SUITABLE DIENOPHILE | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1986-05-07 | — | — | EP | disclosed |
| US-4539153-A | Method of preparing 1 α-hydroxyvitamin D and 1 α-hydroxyprevitamin D compounds, and adducts of a previtamin D or tachysterol compound with a suitable dienophile | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1985-09-03 | — | — | US | disclosed |
| EP-0133259-A2 | Aminoalkyl-substituted benzene derivatives, process for production thereof, and pharmaceutical composition thereof | KOWA COMPANY, LTD. (JP) | 1985-02-20 | — | — | EP | disclosed |
| EP-0114128-A1 | 3-Amino-2-oxo-azetidine derivatives containing in position 1 a nitrogen heterocyclic radical, process for their preparation, their use as therapeutical agents and intermediates for their preparation | ROUSSEL-UCLAF (FR) | 1984-07-25 | — | — | EP | disclosed |
| US-4029881-A | Antibiotic 9-acyl-3\"-thiomethoxymethyl-SF-837 composition and process for preparing the same | MEIJI SEIKA CO., LTD. (JA) | 1977-06-14 | — | — | US | disclosed |