Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.64 |
| ▸ | CES2 | O00748 | 1/20 | 0.64 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 2/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27618558 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| Benzene SCHEMBL6698503 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| SCHEMBL43943 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| Benzene SCHEMBL11066939 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| Benzene SCHEMBL7058395 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| Benzene SCHEMBL10503945 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| Benzene SCHEMBL3421936 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| SCHEMBL9688483 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| SCHEMBL1331954 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 | |
| Benzene SCHEMBL9511700 | 1.00 | CES1 (0.64) | CES1CES2AKR1B1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721606-B1 | PHOTOPOLYMERISABLE COMPOSITION | KODAK POLYCHROME GRAPHICS CO (US) | 2000-03-15 | — | — | EP | claimed |
| US-7989424-B2 | Glucopyranosyloxypyrazole derivatives and use thereof in medicines | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2011-08-02 | — | — | US | disclosed |
| EP-1354888-B1 | GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND USE THEREOF IN MEDICINES | KISSEI PHARMACEUTICAL (JP) | 2009-05-20 | — | — | EP | disclosed |
| US-20090093419-A1 | GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND USE THEREOF IN MEDICINES | KISSEI PHARMACEUTICAL CO. LTD. (JP) | 2009-04-09 | — | — | US | disclosed |
| US-7465713-B2 | Glucopyranosyloxypyrazole derivatives and use thereof in medicines | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-12-16 | — | — | US | disclosed |
| US-7429568-B2 | Antidiabetic agents; human SGLT2 (sodium ion / glucose cotransporter 2) inhibitors; hyperglycemia, obesity; 3-(6-O-ethoxycarbonyl- beta -D-glucopyranosyloxy)-4-[(4-isopropoxyphenyl)methyl]-1-isopropyl-5-methylpyrazole | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-09-30 | — | — | US | disclosed |
| US-7393838-B2 | Glucopyranosyloxypyrazole derivatives and use thereof in medicines | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-01 | — | — | US | disclosed |
| US-7115575-B2 | Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2006-10-03 | — | — | US | disclosed |
| US-7084123-B2 | Glucopyranosyloxypyrazole derivatives and use thereof in medicines | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-01 | — | — | US | disclosed |
| US-7056892-B2 | Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2006-06-06 | — | — | US | disclosed |
| US-20050137143-A1 | Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof | KISSEI PHARMACEUTICAL CO., LTD. | 2005-06-23 | — | — | US | disclosed |
| EP-1213296-B1 | GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES IN THE PRODUCTION THEREOF | KISSEI PHARMACEUTICAL (JP) | 2004-04-14 | — | — | EP | disclosed |
| CN-1145635-C | Glucopyranosyloxypyrazole derivatives, pharmaceutical compositions containing the same and intermediates in their preparation | ����ҩƷ��ҵ��ʽ���� | 2004-04-14 | — | — | CN | disclosed |
| US-20040063646-A1 | Glucopyranosyloxypyrazole derivatives and use thereof in medicines | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1354888-A1 | GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND USE THEREOF IN MEDICINES | Kissei Pharmaceutical Co., Ltd. (JP) | 2003-10-22 | — | — | EP | disclosed |
| CN-1377363-A | Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof | KISSEI PHARMACEUTICAL (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1213296-A1 | GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-4762760-A | FILM ON SUBSTRATE, ADHESION, FLEXIBILITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| US-4463171-A | BACTERICIDES | SANRAKU-OCEAN CO., LTD. (JP) | 1984-07-31 | — | — | US | disclosed |
| US-4436904-A | ANTIBIOTICS, BACTERICIDES | KANTO ISHI PHARMACEUTICAL CO., LTD. (JP) | 1984-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093419-A1 | GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVES AND USE THEREOF IN MEDICINES | SLC5A2, SLC5A1, SLC2A4 | CES1 346/4885CES2 396/4885AKR1B1 532/4885 |
| US-20040063646-A1 | Glucopyranosyloxypyrazole derivatives and use thereof in medicines | SLC5A2, SLC5A1, UGGT1 | CES1 353/4885CES2 424/4885AKR1B1 601/4885 |
| US-20050137143-A1 | Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof | SLC5A1, SLC5A2, UGGT1 | CES1 297/4885CES2 589/4885AKR1B1 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.