Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10504234 | 1.00 | ALDH1A1 (0.40) | ALDH1A1ALOX12USP2LMNAHPGD | |
| SCHEMBL16188092 | 1.00 | ALDH1A1 (0.40) | ALDH1A1ALOX12USP2LMNAHPGD | |
| SCHEMBL12950248 | 0.97 | — | — | |
| SCHEMBL10014680 | 0.97 | — | — | |
| SCHEMBL16188089 | 0.91 | — | — | |
| SCHEMBL16188091 | 0.84 | — | — | |
| SCHEMBL9112173 | 0.78 | ALDH1A1 (0.38) | ALDH1A1ALOX12USP2LMNAHPGD | |
| SCHEMBL9112178 | 0.78 | ALDH1A1 (0.38) | ALDH1A1ALOX12USP2LMNAHPGD | |
| SCHEMBL11798839 | 0.76 | ALDH1A1 (0.41) | ALDH1A1ALOX12USP2LMNAHPGD | |
| SCHEMBL11798830 | 0.76 | ALDH1A1 (0.41) | ALDH1A1ALOX12USP2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163227-B1 | 5-SUBSTITUTED CHROMONES AND THIOCHROMONES | MILES INC. (US) | 1989-08-02 | — | — | EP | disclosed |
| US-4639535-A | INTERMEDIATES FOR ANTIALLERGENS | MILES LABORATORIES, INC. (US) | 1987-01-27 | — | — | US | disclosed |
| US-4571405-A | Anti-allergic chromone- or thiochromone-5-oxamic acid derivatives, compositions, and method of use therefor | MILES LABORATORIES, INC. (US) | 1986-02-18 | — | — | US | disclosed |
| EP-0163227-A1 | 5-Substituted chromones and thiochromones | MILES INC. (US) | 1985-12-04 | — | — | EP | disclosed |