Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2179400 | 0.85 | KDM4E (0.52) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL14562932 | 0.81 | ALDH1A1 (0.50) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL4405073 | 0.81 | ALDH1A1 (0.50) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL2435688 | 0.79 | ALDH1A1 (0.54) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL15826790 | 0.78 | GLA (0.55) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL1889261 | 0.78 | GLA (0.55) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL2201068 | 0.78 | GAA (0.57) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL1726734 | 0.78 | TSHR (0.58) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7341620 | 0.77 | GLA (0.58) | KDM4EGLAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL8190980 | 0.75 | KDM4E (0.50) | KDM4EGLAGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123504-B1 | COMPLEXES OF TECHNETIUM-99M WITH ALKYLENE AMINE OXIMES | AMERSHAM INTERNATIONAL plc (GB) | 1989-09-20 | — | — | EP | disclosed |
| EP-0123504-A2 | Complexes of technetium-99m with alkylene amine oximes | AMERSHAM INTERNATIONAL plc (GB) | 1984-10-31 | — | — | EP | disclosed |