Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515394 | 0.88 | MEN1 (0.53) | MEN1KMT2APOLBHSP90AA1TDP1 | |
| SCHEMBL10915818 | 0.81 | MEN1 (0.51) | MEN1KMT2APOLBHSP90AA1TDP1 | |
| SCHEMBL11094177 | 0.79 | MEN1 (0.53) | MEN1KMT2APOLBHSP90AA1TDP1 | |
| SCHEMBL10666115 | 0.78 | MAPT (0.53) | MEN1KMT2APOLBMAPTKDM4E | |
| SCHEMBL1922823 | 0.77 | MEN1 (0.53) | MEN1KMT2APOLBHSP90AA1TDP1 | |
| SCHEMBL3699829 | 0.76 | MEN1 (0.47) | MEN1KMT2APOLBHSP90AA1TDP1 | |
| SCHEMBL9665078 | 0.76 | MEN1 (0.68) | MEN1KMT2APOLBHSP90AA1TDP1 | |
| SCHEMBL12415429 | 0.74 | KMT2A (0.57) | MEN1KMT2APOLBHSP90AA1TDP1 | |
| SCHEMBL1964353 | 0.73 | MEN1 (0.54) | MEN1KMT2APOLBHSP90AA1TDP1 | |
| SCHEMBL1967149 | 0.73 | MEN1 (0.46) | MEN1KMT2APOLBHSP90AA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163895-B1 | PROCESS FOR THE DIASTEREOSELECTIVE REDUCTION OF ALPHA-TRIAZOLYL KETONES TO BETA-TRIAZOLYL CARBINOLS | BASF Aktiengesellschaft (DE) | 1989-04-12 | — | — | EP | disclosed |
| US-4748250-A | Diastereoselective reduction of alpha-triazolylketones to betatriazolylcarbinols | BASF AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |
| EP-0163895-A1 | Process for the diastereoselective reduction of alpha-triazolyl ketones to beta-triazolyl carbinols | BASF Aktiengesellschaft (DE) | 1985-12-11 | — | — | EP | disclosed |