Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11181063 | 0.88 | MAPT (0.65) | MAPTCYP3A4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10568398 | 0.82 | MAPT (0.62) | MAPTCYP3A4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11089621 | 0.78 | CYP3A4 (0.53) | MAPTCYP3A4POLBKMT2AMEN1 | |
| SCHEMBL10504752 | 0.78 | MEN1 (0.50) | MAPTCYP3A4POLBKMT2AMEN1 | |
| SCHEMBL11169707 | 0.77 | CYP3A4 (0.77) | MAPTCYP3A4POLBKMT2AMEN1 | |
| SCHEMBL12415427 | 0.75 | MAPT (0.60) | MAPTCYP3A4POLBKMT2AMEN1 | |
| SCHEMBL1966676 | 0.73 | MAPT (0.54) | MAPTCYP3A4KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1963735 | 0.73 | MAPT (0.54) | MAPTCYP3A4POLBKMT2AMEN1 | |
| SCHEMBL1923770 | 0.73 | MAPT (0.55) | MAPTCYP3A4POLBKMT2AMEN1 | |
| SCHEMBL1965569 | 0.73 | MAPT (0.53) | MAPTCYP3A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4748250-A | Diastereoselective reduction of alpha-triazolylketones to betatriazolylcarbinols | BASF AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |