Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17208135 | 0.76 | AKR1C3 (0.69) | AKR1C3AKR1C2PTGS1KDM4EMAPT | |
| SCHEMBL9330077 | 0.73 | CNR1 (0.51) | ALDH1A1 | |
| SCHEMBL19506648 | 0.72 | HTR2A (0.56) | AKR1C3AKR1C2PTGS1KDM4EMAPT | |
| SCHEMBL16024600 | 0.72 | HTR2A (0.56) | AKR1C3AKR1C2PTGS1KDM4EMAPT | |
| 6-Methoxy-2-Naphthylacetic Acid SCHEMBL9504307 | 0.72 | AKR1C3 (0.97) | AKR1C3AKR1C2PTGS1KDM4EMAPT | |
| SCHEMBL14783441 | 0.72 | HTR2A (0.56) | AKR1C3AKR1C2PTGS1KDM4EMAPT | |
| SCHEMBL8755746 | 0.72 | AKR1C3 (0.59) | AKR1C3AKR1C2PTGS1KDM4EMAPT | |
| Methane SCHEMBL11454588 | 0.72 | PTGS1 (0.52) | AKR1C3AKR1C2PTGS1KDM4EMAPT | |
| SCHEMBL13653061 | 0.71 | AKR1C3 (0.71) | AKR1C3AKR1C2PTGS1KDM4EMAPT | |
| SCHEMBL7205276 | 0.71 | MMP9 (0.53) | MEN1KMT2AMMP9MMP13ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203557-B1 | PROCESS FOR THE PREPARATION OF (6-METHOXY-2-NAPHTHYL)-(1-BROMOETHYL)-KETONE AND ITS DERIVATIVES | ZAMBON S.p.A. (IT) | 1989-04-19 | — | — | EP | claimed |