MMP9 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL34604	1.00	20/20
Ilomastat (SCHEMBL35303)	1.00	16/20
SCHEMBL54207	0.51	14/20
SCHEMBL48854	0.61	10/20
SCHEMBL49294	0.61	10/20
SCHEMBL49295	0.61	10/20
SCHEMBL48807	0.59	10/20
SCHEMBL48808	0.59	10/20
SCHEMBL54973	0.59	10/20
SCHEMBL48620	0.65	9/20
SCHEMBL48621	0.65	9/20
SCHEMBL48622	0.65	9/20
SCHEMBL48635	0.65	9/20
SCHEMBL48636	0.65	9/20
SCHEMBL49184	0.63	7/20
SCHEMBL49185	0.63	7/20
SCHEMBL49193	0.63	7/20
SCHEMBL26434	0.57	7/20
Butethal (SCHEMBL44262)	0.53	7/20
SCHEMBL32038	0.47	7/20

Clinical trials — most relevant to MMP9 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Doxycycline In Lymphangioleiomyomatosis (LAM)	PHASE4	COMPLETED
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY	PHASE4	SUSPENDED
Hyaluronic Acid vs Mitomycin-C in External Dacryocystorhinostomy	PHASE4	NOT_YET_RECRUITING
Efficacy of Pioglitazone and Metformin on Cardiovascular Risk in Subjects With Insulin-Treated Type 2 Diabetes Mellitus.	PHASE4	COMPLETED
Minocycline for Aneurysmal Subarachnoid Hemorrhage (MASH)	PHASE2	ACTIVE_NOT_RECRUITING
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer	PHASE1	COMPLETED
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial	nan	COMPLETED
Influence of Statins in Artery Aneurysms	nan	UNKNOWN
Characterizing the Inflammation Around Dental Implants: Bacterial Infection, Hypersensitivity or Both?	nan	RECRUITING
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer	nan	COMPLETED
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction	nan	COMPLETED
Periodontal Health in Post COVID-19 Patients	nan	UNKNOWN
Influence of Exercise Program on Serum Matrix Metalloproteinases and Functional Status in Women With Postmenopausal Osteoporosis	nan	COMPLETED
Evaluation of Dentinal Fluid for the Presence of Matrix Metalloproteinase 9 (MMP-9) in Pulpal Inflammation	nan	COMPLETED
Matrix Metalloproteinases 7 and 9 in Rheumatoid Arthritis Patients With Interstitial Lung Disease	nan	NOT_YET_RECRUITING
The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis	nan	RECRUITING
Matrix Metalloproteinases's in Oral Biofluids During Pregnancy and Postpartum	nan	COMPLETED
Abnormal 3-D MRI Flow Patterns in Adolescents Patients With Bicuspid Aortic Valve	nan	COMPLETED
Hypoxia-induced Autophagy in the Pathogenesis of MAP	nan	UNKNOWN
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels	nan	COMPLETED
miRNA-452 in Patients With Preeclampsia and Its Correlation With MMP-9	nan	COMPLETED
Association Between Matrix Metalloproteinase-2 Gene Polymorphism rs243865 and Susceptibility to Cataract Development	nan	COMPLETED
Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar	nan	COMPLETED
Pathology, Venous Disease, and Clinical Correlations	nan	UNKNOWN
Peri-implantitis and MMP-8	nan	COMPLETED
Biomarkers for Prognosis of Glioblastoma (GBM)	nan	COMPLETED
MMP Polymorphisms and Acute Coronary Syndromes	nan	COMPLETED
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects	nan	AVAILABLE
Matrix Metalloproteinase (MMP) in Heart Failure	nan	COMPLETED
Plasma and Scarring of Diabetic Ulcers	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a MMP9 binder may also engage these)

Protein	Name	Similarity
P52176	—	1.000	P52176 →
P41245	—	1.000	P41245 →
P41246	—	1.000	P41246 →
O18733	—	1.000	O18733 →
P50282	—	0.999	P50282 →
P50757	—	0.998	P50757 →
Q95220	—	0.998	Q95220 →
Q9GLE5	—	0.997	Q9GLE5 →
MMP14	Matrix metalloproteinase-14	0.997	landscape →
P53690	—	0.996	P53690 →
P33434	—	0.995	P33434 →
MMP2	72 kDa type IV collagenase	0.995	landscape →
Q10739	—	0.995	Q10739 →
Q5RES1	—	0.994	Q5RES1 →
P33436	—	0.994	P33436 →
Q9GLE4	—	0.994	Q9GLE4 →
O54732	—	0.993	O54732 →
MMP24	Matrix metalloproteinase-24	0.993	landscape →
Q3U435	—	0.992	Q3U435 →
Q9WTR0	—	0.992	Q9WTR0 →
Q9XT90	—	0.991	Q9XT90 →
O18767	—	0.991	O18767 →
Q90611	—	0.991	Q90611 →
Q9EPL5	—	0.990	Q9EPL5 →
Q6Y4Q5	—	0.990	Q6Y4Q5 →
MMP15	Matrix metalloproteinase-15	0.990	landscape →
MMP3	Stromelysin-1	0.990	landscape →
O88917	—	0.990	O88917 →
Q11005	—	0.990	Q11005 →
O55123	—	0.990	O55123 →