Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10508682 | 0.92 | HPGD (0.43) | HPGDHTTTSHRALOX5NLRP3 | |
| SCHEMBL10509426 | 0.90 | TSHR (0.50) | HPGDHTTTSHRALOX5HCRTR1 | |
| SCHEMBL10506059 | 0.89 | TSHR (0.46) | HPGDHTTTSHRALOX5HCRTR1 | |
| SCHEMBL10506672 | 0.88 | TSHR (0.45) | HPGDHTTTSHRALOX5HCRTR1 | |
| SCHEMBL10506261 | 0.88 | TSHR (0.45) | HPGDHTTTSHRALOX5HCRTR1 | |
| SCHEMBL10507471 | 0.84 | DRD3 (0.50) | HPGDALDH1A1NPC1 | |
| SCHEMBL10510182 | 0.84 | P2RX7 (0.50) | HPGDHTTTSHRALOX5NPC1 | |
| SCHEMBL10510261 | 0.84 | TSHR (0.53) | HPGDHTTTSHRALOX5HCRTR1 | |
| SCHEMBL10508432 | 0.84 | HPGD (0.54) | HPGDTSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10507470 | 0.84 | HCRTR1 (0.56) | HPGDHTTTSHRHCRTR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0155810-B1 | N-(OMEGA-GLYCIDOXYALKYL)-SUBSTITUTED AMIDE COMPOUNDS AND PREPARATION PROCESS THEREOF | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0155810-A2 | N-(omega-glycidoxyalkyl)-substituted amide compounds and preparation process thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1985-09-25 | — | — | EP | disclosed |