SCHEMBL10506282

SCHEMBL10506282

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nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.43
TSHR P16473 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10506288 1.00 TDP1 (0.43) TDP1TSHRTRPV1ALOX15
SCHEMBL10507699 1.00 TDP1 (0.43) TDP1TSHRTRPV1ALOX15
SCHEMBL10511575 1.00 TDP1 (0.43) TDP1TSHRTRPV1ALOX15
SCHEMBL10507704 1.00 TDP1 (0.43) TDP1TSHRTRPV1ALOX15
SCHEMBL10509214 0.86 TDP1 (0.38) TDP1TSHRTRPV1
SCHEMBL5792082 0.82 TDP1 (0.68) TDP1TSHRTRPV1ALOX15
SCHEMBL8371313 0.82 TDP1 (0.68) TDP1TSHRTRPV1ALOX15
SCHEMBL7566395 0.82 TDP1 (0.68) TDP1TSHRTRPV1ALOX15
SCHEMBL15892789 0.82 TDP1 (0.59) TDP1TSHRTRPV1ALOX15
SCHEMBL7320301 0.81 TDP1 (0.43) TDP1TSHRTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0173462-B1 ELLIPTICINE DERIVATIVE AND PRODUCTION PROCESS THEREOF SUNTORY LIMITED (JP) 1989-10-25 EP disclosed
US-4698423-A ANTITUMOR AGENTS SUNTORY LIMITED (JP) 1987-10-06 US disclosed
EP-0173462-A2 Ellipticine derivative and production process thereof SUNTORY LIMITED (JP) 1986-03-05 EP disclosed