Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570593 | 1.00 | TDP1 (0.43) | TDP1TSHRTRPV1CHRM2CHRM4 | |
| SCHEMBL10506288 | 0.81 | TDP1 (0.43) | TDP1TSHRTRPV1 | |
| SCHEMBL10506282 | 0.81 | TDP1 (0.43) | TDP1TSHRTRPV1 | |
| SCHEMBL10507704 | 0.81 | TDP1 (0.43) | TDP1TSHRTRPV1 | |
| SCHEMBL10507699 | 0.81 | TDP1 (0.43) | TDP1TSHRTRPV1 | |
| SCHEMBL10511575 | 0.81 | TDP1 (0.43) | TDP1TSHRTRPV1 | |
| SCHEMBL570751 | 0.79 | TDP1 (0.44) | TDP1TSHRTRPV1 | |
| SCHEMBL5792082 | 0.79 | TDP1 (0.68) | TDP1TSHRTRPV1 | |
| SCHEMBL7566395 | 0.79 | TDP1 (0.68) | TDP1TSHRTRPV1 | |
| SCHEMBL8371313 | 0.79 | TDP1 (0.68) | TDP1TSHRTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310519-B1 | ANDROSTANE 17-CARBOXYLIC-ACID ESTERS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | LABORATOIRE NATIVELLE (Société Anonyme) (FR) | 1992-08-19 | — | — | EP | claimed |
| US-4885280-A | CARDIOTONIC AGENTS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1989-12-05 | — | — | US | claimed |
| US-4885280-A | CARDIOTONIC AGENTS | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1989-12-05 | — | — | US | disclosed |