Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10506342 | 0.90 | PDE5A (0.35) | PDE5AMEN1KMT2AHPGDPPARG | |
| SCHEMBL10506065 | 0.86 | PDE5A (0.44) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL10507784 | 0.84 | MAOB (0.43) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL10506947 | 0.83 | CYSLTR2 (0.42) | HTTSMN1; SMN2KDM4ETP53CYP2D6 | |
| SCHEMBL9204366 | 0.77 | PDE5A (0.33) | PDE5AMEN1KMT2AHPGDPPARG | |
| SCHEMBL10504963 | 0.77 | PDE5A (0.46) | KDM4EPDE5AMEN1KMT2AHPGD | |
| SCHEMBL10509864 | 0.73 | PDE5A (0.39) | KDM4EPDE5AMEN1KMT2AHPGD | |
| SCHEMBL10507930 | 0.73 | CYSLTR2 (0.44) | KDM4EPDE5AMEN1KMT2AHPGD | |
| SCHEMBL10506675 | 0.72 | PDE5A (0.36) | KDM4EPDE5AMEN1KMT2AHPGD | |
| SCHEMBL10505286 | 0.72 | KDM4E (0.47) | HTTSMN1; SMN2KDM4ETP53CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150966-B1 | BENZOPYRAN DERIVATIVES, COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION | FISONS plc (GB) | 1989-07-12 | — | — | EP | claimed |