Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10506342 | 0.82 | PDE5A (0.35) | PDE5APPARGPPARAMEN1MAPT | |
| SCHEMBL10509864 | 0.77 | PDE5A (0.39) | PDE5APPARGPPARAMEN1MAPT | |
| SCHEMBL10510661 | 0.77 | PDE5A (0.35) | PDE5APPARGPPARAMEN1MAPT | |
| SCHEMBL10507166 | 0.77 | HTT (0.37) | PDE5APPARGPPARAMEN1MAPT | |
| SCHEMBL10506675 | 0.76 | PDE5A (0.36) | PDE5APPARGPPARAMEN1MAPT | |
| SCHEMBL11066772 | 0.76 | LMNA (0.41) | MEN1MAPTHPGDKMT2A | |
| Nedocromil SCHEMBL4611 | 0.73 | PDE5A (0.47) | PDE5AMEN1MAPTHPGDTBXAS1 | |
| Nedocromil SCHEMBL29406688 | 0.73 | PDE5A (0.47) | PDE5AMEN1MAPTHPGDTBXAS1 | |
| Nedocromil SCHEMBL667050 | 0.72 | PDE5A (0.46) | PDE5AMEN1MAPTHPGDTBXAS1 | |
| SCHEMBL10507162 | 0.72 | PDE5A (0.35) | PDE5APPARGPPARAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365119-B1 | Pharmaceutical composition | FISONS PLC (GB) | 1994-11-30 | — | — | EP | claimed |
| EP-0279121-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING AN AQUEOUS SOLUTION OF A PYRANOQUINOLINE DERIVATIVE | FISONS plc (GB) | 1993-09-01 | — | — | EP | claimed |
| EP-0285246-B1 | Calcium-4,6-dioxo-4h-pyrano[3,2-g]-quinoline-2,8-dicarboxylate derivative, methods for its preparation and compositions containing it | FISONS plc (GB) | 1992-01-02 | — | — | EP | claimed |
| EP-0294940-B1 | PHARMACEUTICAL COMPOSITIONS | FISONS plc (GB) | 1991-12-11 | — | — | EP | claimed |
| EP-0241134-B1 | PHARMACEUTICAL MIXTURE COMPRISING NEDOCROMIL OR A SALT THEREOF IN COMBINATION WITH A BRONCHODILATOR | FISONS plc (GB) | 1991-10-30 | — | — | EP | claimed |
| EP-0400522-B1 | Process for the preparation of micronised biodegradable particles | BOEHRINGER INGELHEIM KG (DE) | 1995-01-04 | — | — | EP | disclosed |
| EP-0400522-A2 | Process for the preparation of micronised biodegradable particles | BOEHRINGER INGELHEIM KG (DE) | 1990-12-05 | — | — | EP | disclosed |