SCHEMBL1050786

SCHEMBL1050786

COCC(C)NC(C)COC

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.35
KDM4E B2RXH2 3/20 0.35
CYP2D6 P10635 1/20 0.34
HPGD P15428 3/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
HCAR3 P49019 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HSD17B10 Q99714 1/20 0.31
SLC6A4 P31645 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3551089 0.88
SCHEMBL12870189 0.88
SCHEMBL18412739 0.88
SCHEMBL24279166 0.87 ALDH1A1 (0.33) ALDH1A1KDM4ECYP2D6HPGDHTT
SCHEMBL21129089 0.87 ALDH1A1 (0.33) ALDH1A1KDM4ECYP2D6HPGDHTT
SCHEMBL24279174 0.87 ALDH1A1 (0.33) ALDH1A1KDM4ECYP2D6HPGDHTT
SCHEMBL3435730 0.78
SCHEMBL75912 0.78
SCHEMBL3435692 0.78
SCHEMBL24239378 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110621653-B Amino (meth) acrylates 湛新比利时股份有限公司 2022-09-16 CN disclosed
US-11318120-B2 Nuclear transport modulators and uses thereof BIOGEN MA INC. (US) 2022-05-03 US disclosed
US-20210251968-A1 NUCLEAR TRANSPORT MODULATORS AND USES THEREOF BIOGEN MA INC. (US) 2021-08-19 US disclosed
EP-2032115-B1 COMPOSITIONS BASED ON HYPERBRANCHED CONDENSATION POLYMERS AND NOVEL HYPERBRANCHED CONDENSATION POLYMERS DSM IP ASSETS BV (NL) 2021-07-21 EP disclosed
CN-110621653-A Amino (meth) acrylates 湛新比利时股份有限公司 2019-12-27 CN disclosed
EP-1991604-B1 NOVEL HETEROCYCLIC SUBSTITUTED CONDENSATION POLYMERS DSM IP ASSETS BV (NL) 2018-03-28 EP disclosed
EP-2454312-B1 RESINS AND COATING COMPOSITIONS DSM IP ASSETS BV (NL) 2017-03-01 EP disclosed
US-8999494-B2 Resins and coating compositions DSM IP ASSETS B.V. (NL) 2015-04-07 US disclosed
US-8951509-B2 Heterocyclic substituted condensation polymers DSM IP ASSETS B.V. (NL) 2015-02-10 US disclosed
US-8394500-B2 Compositions based on hyperbranched condensation polymers and novel hyperbranched condensation polymers DSM IP ASSETS B.V. (NL) 2013-03-12 US disclosed
WO-2007144189-A2 COMPOSITIONS BASED ON HYPERBRANCHED CONDENSATION POLYMERS AND NOVEL HYPERBRANCHED CONDENSATION POLYMERS DSM IP ASSETS B.V. (NL) 2007-12-21 WO disclosed
WO-2007098889-A1 NOVEL HETEROCYCLIC SUBSTITUTED CONDENSATION POLYMERS DSM IP ASSETS B.V. (NL) 2007-09-07 WO disclosed
US-6730771-B2 THERMOPLASTIC, THERMOSETTING RESINS DSM N.V. (NL) 2004-05-04 US disclosed
EP-1171510-B1 CONDENSATION POLYMER CONTAINING DIALKYLAMIDE ENDGROUPS, PROCESS FOR PRODUCING SAID CONDENSATION POLYMERS AND APPLICATIONS THEREOF DSM IP ASSETS BV (NL) 2003-11-05 EP disclosed
US-6541110-B2 Endcapped polyamideester copolymers; compatible blend with another polymer DSM N.V. (NL) 2003-04-01 US disclosed
US-20020137880-A1 Condensation polymer containing dialkylamide endgroups, process for producing said condensation polymers and applications thereof DSM IP ASSETS B.V. (NL) 2002-09-26 US disclosed
US-20020019509-A1 Condensation polymer containing dialkylamide endgroups, process for producing said condensation polymers and applications thereof DSM N.V. (NL) 2002-02-14 US disclosed
EP-1171510-A1 CONDENSATION POLYMER CONTAINING DIALKYLAMIDE ENDGROUPS, PROCESS FOR PRODUCING SAID CONDENSATION POLYMERS AND APPLICATIONS THEREOF DSM N.V. (NL) 2002-01-16 EP disclosed
WO-2000058388-A1 CONDENSATION POLYMER CONTAINING DIALKYLAMIDE ENDGROUPS, PROCESS FOR PRODUCING SAID CONDENSATION POLYMERS AND APPLICATIONS THEREOF DSM N.V. (NL) 2000-10-05 WO disclosed
EP-1038902-A1 Condensation polymers containing dialkylamide endgroups, process for their production and applications thereof DSM N.V. (NL) 2000-09-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210251968-A1 NUCLEAR TRANSPORT MODULATORS AND USES THEREOF XPO1, XPO5, XPOT ALDH1A1 3151/4885KDM4E 2315/4885CYP2D6 1762/4885
US-11318120-B2 Nuclear transport modulators and uses thereof XPO1, XPO5, XPOT ALDH1A1 3151/4885KDM4E 2315/4885CYP2D6 1762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.