Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12313578 | 0.84 | SLC6A4 (0.68) | SLC6A4 | |
| SCHEMBL10345906 | 0.80 | SLC6A4 (0.68) | POLBSLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6196209 | 0.79 | POLB (0.55) | POLBSLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2803387 | 0.77 | POLB (0.45) | POLBSLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL12190892 | 0.76 | POLB (0.52) | POLBSLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL746669 | 0.75 | POLB (0.55) | POLBSLC6A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28266229 | 0.75 | POLB (0.55) | POLBCYP1A2CYP2D6CYP2C19GAA | |
| SCHEMBL2803084 | 0.75 | POLB (0.60) | POLBCYP1A2ACACBPARP10ALDH1A1 | |
| SCHEMBL19759402 | 0.75 | POLB (0.60) | POLBCYP1A2ACACBPARP10ALDH1A1 | |
| SCHEMBL14449300 | 0.74 | POLB (0.59) | POLBCYP1A2CYP2D6CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163948-B1 | PROCESS FOR PRODUCING AN INDOLINE | IHARA CHEMICAL IND CO | 1989-08-16 | — | — | EP | disclosed |
| US-4673749-A | CYCLIZATION OF 2-HOLOGENO PHENETHYLAMINES WITH COPPER CATALYS T AND ALKALI DEHYROHALOGENATING AGENT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-06-16 | — | — | US | disclosed |
| EP-0163948-A1 | Process for producing an indoline | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 1985-12-11 | — | — | EP | disclosed |
| US-4280958-A | COPPER-TYPE CATALYST USED IN CYCLIZATION OF A HALOGENOPHENETHYLAMINE IN THE PRESENCE OF AN AMINE | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-07-28 | — | — | US | disclosed |