Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.58 |
| ▸ | ACACA | Q13085 | 3/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TACR3 | P29371 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10506477 | 0.87 | KDM4E (0.61) | KDM4ELMNASMN1; SMN2PDE10AACACA | |
| SCHEMBL10509237 | 0.85 | KDM4E (0.55) | KDM4ELMNASMN1; SMN2PDE10AACACA | |
| SCHEMBL13268004 | 0.81 | KDM4E (0.54) | KDM4ELMNASMN1; SMN2PDE10ADHODH | |
| SCHEMBL1259674 | 0.80 | ACHE (0.59) | KDM4ELMNASMN1; SMN2PDE10AACACA | |
| SCHEMBL13821792 | 0.79 | PLA2G10 (0.48) | KDM4ESMN1; SMN2ACACAACHECYP3A4 | |
| SCHEMBL2998020 | 0.79 | KDM4E (0.50) | KDM4EACACAACHECYP3A4HPGD | |
| SCHEMBL10675180 | 0.79 | KDM4E (0.76) | KDM4ELMNASMN1; SMN2PDE10ACYP2C9 | |
| SCHEMBL10677865 | 0.79 | KDM4E (0.54) | KDM4ELMNASMN1; SMN2PDE10ADHODH | |
| SCHEMBL13243228 | 0.78 | ESRRB (0.59) | KDM4ELMNASMN1; SMN2PDE10AACACA | |
| SCHEMBL3968020 | 0.78 | ACHE (0.58) | KDM4ELMNASMN1; SMN2PDE10AACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210084-B1 | AMIDES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1989-02-08 | — | — | EP | disclosed |
| EP-0210084-A1 | Amides, processes for their preparation and medicaments containing them | RHONE-POULENC SANTE (FR) | 1987-01-28 | — | — | EP | disclosed |